General Information

  • ID:  hor003558
  • Uniprot ID:  P84661
  • Protein name:  Periviscerokinin-3
  • Gene name:  NA
  • Organism:  Aptera fusca (Cape Mountain cockroach) (Giant Table Mountain cockroach)
  • Family:  Periviscerokinin family
  • Source:  Animal
  • Expression:  Expressed in abdominal perisympathetic organs and abdominal ganglia.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Aptera (genus), Epilamprinae (subfamily), Blaberidae (family), Blaberoidea (superfamily), Blattodea (order), Dictyoptera (superorder), Polyneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  GSSGIIPFPRV
  • Length:  11(1-11)
  • Propeptide:  GSSGIIPFPRV
  • Signal peptide:  NA
  • Modification:  T11 Valine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003558_AF2.pdbhor003558_ESM.pdb

Physical Information

Mass: 130786 Formula: C52H84N14O14
Absent amino acids: ACDEHKLMNQTWY Common amino acids: GIPS
pI: 10.55 Basic residues: 1
Polar residues: 4 Hydrophobic residues: 4
Hydrophobicity: 53.64 Boman Index: -298
Half-Life / Aliphatic Index: 30 hour Aliphatic Index: 97.27
Instability Index: 4442.73 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  19257902
  • Title:  A proteomic approach for studying insect phylogeny: CAPA peptides of ancient insect taxa (Dictyoptera, Blattoptera) as a test case.